MORPHOLOGY-BASED MODELLING OF PENICILLIUM CHRYSOGENUM FED-BATCH CULTIVATIONS

Abstract

The presented models combine microscopic and macroscopic descriptions of pellet development. There are still some assumptions in the model which are difficult to verify experimentally like the inactivation of the biomass as a consequence of mechanical damage. However, we presented a novel approach which allows to study influences on the overall process such as substrate limitations within the pellets, hyphal morphology or mechanical forces.