Investigation of the preparation of cycloalkanoindole derivative in ionic solvent

Authors

  • Katalin Kupai
    Affiliation
    Department of Organic Chemistry and Technology, Budapest University of Technology and Economics
  • Gábor Hornyánszky
    Affiliation
    Department of Organic Chemistry and Technology, Budapest University of Technology and Economics
  • Lajos Novák
https://doi.org/10.3311/PPch.2170

Abstract

Optimization of the synthesis of carba analogs of physostigmine is described. Aza-Claisen-rearrangement, followed by aza-Alder-ene reaction of aniline derivatives gave the title product besides some byproduct. The effects of the amounts of catalyst, solvent, temperature and the method of heating were investigated.

Keywords:

aza-Claisen rearrangement, aza-Alder-ene reaction, ionic solvent, optimization

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Published Online

2013-06-26

How to Cite

Kupai, K., Hornyánszky, G., Novák, L. “Investigation of the preparation of cycloalkanoindole derivative in ionic solvent”, Periodica Polytechnica Chemical Engineering, 57(1-2), pp. 53–54, 2013. https://doi.org/10.3311/PPch.2170

Issue

Vol. 57 No. 1-2 (2013)

Section

Articles