Structure-resolvability relationship of several diastereomeric salt pairs of 1-phenylethylamine - A Cambridge Structural Database study

Abstract

In order to study the effects of crystal structures on resolvability, a CSD (Cambridge Crystallographic Database) study has been carried out on 1-phenylethylammonium diastereomeric salt pairs with available crystal structures. The structures of the diastereomers of the salts are analyzed, compared and grouped. The structural features are set against the resolution results. The effects of three types of structural features on the resolution efficiency are demonstrated.